Ceramic Ha Resin

Ceramic hydroxyapatite cht ceramic hydroxyapatite types i and ii are produced. These mixed mode resins can be used at any stage in a chromatographic workflow from initial capture to final polishing and are ideal for the purification of monoclonal antibody mab products. Hydroxyapatite also called hydroxylapatite ha is a naturally occurring mineral form of calcium apatite with the formula ca 5 po 4 3 oh but it is usually written ca 10 po 4 6 oh 2 to denote that the crystal unit cell comprises two entities.

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The duration and temperature of the sintering step determine whether the ceramic hydroxyapatite is cht type i or type ii.

Ceramic ha resin.

Its mixed mode support offers unique selectivities and often separates biomolecules that appear homogeneous using other chromatographic methods. Cht ceramic hydroxyapatite is a spherical macroporous form of hydroxyapatite. Hydroxyapatite is the hydroxyl endmember of the complex apatite group the oh ion can be replaced by fluoride chloride or carbonate. This mixed mode support offers unique selectivities and often separates biomolecules that appear homogeneous using other chromatographic methods.

Cht is a mixed mode resin. Cht ceramic hydroxyapatite support is a leading purification medium for today s demanding downstream process industry. Details of the binding mechanism are described in chapter 3. Cht ceramic hydroxyapatite ca 5 po 4 3 oh 2 support is a leading purification medium for today s demanding downstream process industry.

The ceramic material overcomes many of the limitations of traditional crystalline hydroxyapatite that prevent its use in industrial scale applications. It has been sintered at high temperatures to modify it from a crystalline to a ceramic form. Cht ceramic hydroxyapatite and bio gel crystalline hydroxyapatite resins offer unique selectivities enabling the resolution of mixtures that appear homogenous with other media. Jul 26 2020 orchard pottery pottery devon handmade pottery devon handmade stoneware devon handmade resin devon handmade bronze devon.

Cht is a leading purification medium of biomolecules.

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